1622. Outcomes of Colistin Weight-Based Dosing Versus The Non-Weight-Based Dosing
نویسندگان
چکیده
منابع مشابه
Weight-based dosing in medication use: what should we know?
BACKGROUND Weight-based dosing strategy is still challenging due to poor awareness and adherence. It is necessary to let clinicians know of the latest developments in this respect and the correct circumstances in which weight-based dosing is of clinical relevance. METHODS A literature search was conducted using PubMed. RESULTS Clinical indications, physiological factors, and types of medica...
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BACKGROUND/AIMS Growth Hormone (GH) dosage in childhood is adjusted for body size, but there is no consensus whether body weight (BW) or body surface area (BSA) should be used. We aimed at comparing the biological effect and cost-effectiveness of GH treatment dosed per m2 BSA in comparison with dosing per kg BW in girls with Turner syndrome (TS). METHODS Serum IGF-I, GH dose, and adult height...
متن کاملThe effect of weight-based chemotherapy dosing in a cohort of gynecologic oncology patients.
OBJECTIVE Many clinicians limit chemotherapy doses based on a maximum body surface area (BSA) of 2m(2). We sought to determine how chemotherapy-related toxicities compared between groups of patients that varied with respect to BSA. We hypothesized that obese patients receiving weight-based (WB) dosing would not have significantly higher chemotherapy-related toxicities than control groups. MET...
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BACKGROUND: Nephrotoxicity has been a major long-standing concern about colistin. This study was designed to compare nephrotoxicity of high dose and conventional dose of colistin. METHODS: A randomized open-labeled clinical trial on 40 patients with multi-drug resistant gram negative infections was designed. Patients were allocated into two equal-size groups receiving high and conventional dose...
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Correspondence Since no exact threshold accurately predicts an outcome or obligates specifi c management, any selection of cutoffs is arbitrary, whether based on fraction of the hemithorax or actual volume. Separation into thirds 2 or use of quartiles, as suggested by Drs Hu and Zhong, are both, to our knowledge, without precedent. We designed our cutoffs rationally, with no a priori assumption...
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ژورنال
عنوان ژورنال: Open Forum Infectious Diseases
سال: 2020
ISSN: 2328-8957
DOI: 10.1093/ofid/ofaa439.1802